Introducing Flow-Sync

For decades, ECMO simulation has worked the same way:

adjust a setting… wait… watch the monitor react.

But real physiology doesn’t wait.

In the ICU, haemodynamics respond instantly to changes in flow, pressure, oxygen delivery, and venous return. Clinicians interpret patterns, waveforms, and subtle trends, not just numbers.

Until now, simulation could not fully replicate that behaviour.

Today, that changes.

We are proud to introduce Flow-Sync, a breakthrough in ECMO simulation built into the H-SIM App and the E-SIM platform.

Flow-Sync marks the shift from reactive simulation to responsive physiology.

From Reactive to Responsive

Traditional simulators respond after a change is made.

Flow-Sync responds with the change.

By continuously reading live ECMO pump flow, Flow-Sync synchronises haemodynamics and blood gases instantly across the simulation environment.

The result is a new generation of ECMO simulation where:

    •    ECMO flow drives physiology in real time

    •    Waveforms shift naturally with pump adjustments

    •    Haemodynamics evolve smoothly rather than in steps

    •    Clinical patterns appear as they do in real patients

The simulator no longer reacts to the scenario.

It responds to physiology.

A New Level of Haemodynamic Realism

Flow-Sync is powered by a completely new haemodynamic waveform engine.

Instead of abrupt parameter changes, physiology now evolves smoothly and progressively, creating subtle waveform behaviour that mirrors real cardiovascular dynamics.

Small changes in flow, pressure, or therapy now produce natural physiological responses—just as clinicians observe at the bedside.

The difference is immediately visible.

Waveforms feel alive.

Trends make sense.

Simulation finally behaves like physiology.

Built for the ECMO Ecosystem

Flow-Sync integrates seamlessly across the E-SIM platform and connects with ECMO systems used in real training environments.

It works with:

    •    E-SIM Pro 3

    •    E-SIM Portable

    •    Pump-E

    •    Any ECMO system

This allows training centres to connect Flow-Sync directly to their existing ECMO equipment, enabling the simulator to translate pump flow into realistic physiological behaviour in real time.

Beyond Flow

Flow-Sync also introduces a new generation of physiological intelligence within the H-SIM platform, including:

    •    Enhanced haemodynamic waveform modelling

    •    Improved ABG and EtCO₂ behaviour

    •    Realistic cavitation effects on venous return

    •    More accurate drug responses

    •    Expanded integration across the E-SIM ecosystem

Together, these advancements move ECMO simulation closer to true physiological modelling.

About The Simulator Company

The Simulator Company, based in London, is the world’s largest, most innovative, and most awarded ECMO simulator company.

Our technologies—including E-SIM Pro 3, E-SIM Portable, Pump-E, H-SIM, CAN-SIM, U-SIM, LVAD Mini and more—are used by hospitals, universities, and training centres worldwide to train clinicians in advanced circulatory support.

Our mission is simple:

to bring simulation as close as possible to real physiology.

With the introduction of Flow-Sync™, we take another major step toward that goal.

The Future Doesn’t React.

It Responds.

Flow-Sync is now available in the latest release of the H-SIM App and E-SIM platform.

The era of reactive ECMO simulation is over.

The future responds.